Current status of immune check point inhibitors for solid malignancy

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Current status of SRC inhibitors in solid tumor malignancies.

SUMMARY Src is believed to play an important role in cancer, and several agents targeting Src are in clinical development. DESIGN We reviewed Src structure and function and preclinical data supporting its role in the development of cancer via a PubMed search. We conducted an extensive review of Src inhibitors by searching abstracts from major oncology meeting databases in the last 3 years and...

متن کامل

Current Status of Immune Checkpoint Inhibitors in Gastrointestinal Cancers

The expansion of our understanding of tumor immunity and the recent success of new cancer immunotherapy has reignited the hope that we can treat cancer effectively with immunotherapeutic approaches. Immune checkpoint inhibitors have shown significant efficacy in the treatment of some solid and hematologic malignancies. Encouraged by recent success in some other types of malignancies, many clini...

متن کامل

Immune checkpoint inhibitors in large cell neuroendocrine carcinoma: current status

Introduction Large cell neuroendocrine carcinomas (LCNEC) are a group of rare high grade neuroendocrine tumors that often behave clinically like small cell carcinoma (SCLC) and are treated as such. No major advancement in the management of these tumors has occurred in the last 30 years. Methods We present a case series of three cases from Markey Cancer center along with a review of 13 publish...

متن کامل

Immune Check Point Inhibitors in Cancer Therapy: Beware of "Friendly Fire" Effect.

Immune Check Point Inhibitors in Cancer Therapy: Beware of “Friendly Fire” Effect Anuhya Kommalapati1, Shanaz Sikder2 and Sri Harsha Tella3* 1Department of Internal Medicine, Washington Hospital Center, Washington DC, USA 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, USA 3Eunice Kennedy Shriver National Institutes of Child Health and Human Development...

متن کامل

Ablation of pulmonary malignancy: current status.

Since the first reported use of radiofrequency ablation of the lung in 2000, the field of image-guided lung ablation has received a considerable amount of attention. Survival studies have demonstrated the potential utility of thermal ablation in the treatment of patients with early-stage primary and limited secondary pulmonary tumors with promising results. Diagnostic imaging studies have advan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2016

ISSN: 0923-7534

DOI: 10.1093/annonc/mdw453